Open access peer-reviewed Edited Volume

Composition and Function of the Extracellular Matrix in the Human Body

The extracellular matrix (ECM) is an ensemble of non-cellular components present within all tissues and organs of the human body. The ECM provides structural support for scaffolding cellular constituents and biochemical and biomechanical support for those events leading to tissue morphogenesis, differentiation and homeostasis. Essential components of all ECMs are water, proteins and polysaccharides. However, their composition, architecture and bioactivity greatly vary from tissue to tissue in relation to the specific role the ECM is required to assume. This book overviews the role of the ECM in different tissues and organs of the human body.

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Composition and Function of the Extracellular Matrix in the Human BodyEdited by Francesco Travascio

Published: June 15th 2016

DOI: 10.5772/61601

ISBN: 978-953-51-2416-0

Print ISBN: 978-953-51-2415-3

eBook (PDF) ISBN: 978-953-51-5433-4

Copyright year: 2016

Books open for chapter submissions

25767 Total Chapter Downloads

29 Crossref Citations

48 Web of Science Citations

88 Dimensions Citations


Open access peer-reviewed

1. The Importance of Extracellular Matrix in Skeletal Muscle Development and Function

By Katarzyna Grzelkowska-Kowalczyk


Open access peer-reviewed

2. Composition and Function of Extracellular Matrix in Development of Skeletal Muscle

By Zishuai Wang and Zhonglin Tang


Open access peer-reviewed

3. Remodelling of Skeletal Muscle Extracellular Matrix: Effect of Unloading and Reloading

By Eva-Maria Riso, Priit Kaasik and Teet Seene


Open access peer-reviewed

4. The Extracellular Matrix Complexome from Skeletal Muscle

By Sandra Murphy and Kay Ohlendieck


Open access peer-reviewed

5. The Extracellular Matrix in the Nervous System: The Good and the Bad Aspects

By Elena Vecino and Jessica C. F. Kwok


Open access peer-reviewed

6. The Mosaic of Extracellular Matrix in the Central Nervous System as a Determinant of Glial Heterogeneity

By Cory M. Willis and Stephen J. Crocker


Open access peer-reviewed

7. Neuronal Plasticity in the Juvenile and Adult Brain Regulated by the Extracellular Matrix

By Max F.K. Happel and Renato Frischknecht


Open access peer-reviewed

8. CCN Family: Matricellular Proteins in Cartilage and Bone Development

By John A. Arnott, Kathleen Doane and Sonia Lobo Planey


Open access peer-reviewed

9. Biophysical Properties of the Basal Lamina: A Highly Selective Extracellular Matrix

By Fabienna Arends and Oliver Lieleg


Open access peer-reviewed

10. The Role of Extracellular Matrix Proteins in the Urinary Tract: A Literature Review

By Cevdet Kaya and Bahadır Şahin


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11. Mechanisms of Collagen Network Organization in Response to Tissue/Organ Damage

By Takaoki Saneyasu, Saeko Yoshioka and Takao Sakai


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12. Tumor Microenvironment Heterogeneity: A Review of the Biology Masterpiece, Evaluation Systems, and Therapeutic Implications

By Irene Tadeo, Tomás Álvaro, Samuel Navarro and Rosa Noguera


Open access peer-reviewed

13. Exploring the Extracellular Matrix to Create Biomaterials

By Sylvain Vigier and Tamas Fülöp


Open access peer-reviewed

14. Extracellular Matrix Enhances Therapeutic Effects of Stem Cells in Regenerative Medicine

By Yan Nie, Shuaiqiang Zhang, Na Liu and Zongjin Li


Open access peer-reviewed

15. New and Improved Tissue Engineering Techniques: Production of Exogenous Material-Free Stroma by the Self-Assembly Technique

By Ingrid Saba, Weronika Jakubowska, Stéphane Chabaud and Stéphane Bolduc


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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