Open access peer-reviewed Edited Volume


Edited by Sekar Ashok Kumar

Anna University, Chennai, India

This book is aimed to accentuate the importance of hypercholesterolemia, since targeting and treating the hypercholesterolemia is increasingly well known as an essential strategy in the prevention of atherosclerosis-induced cardiovascular disease. It is important to look at hypercholesterolemia as it is proved to be crucial as well as the early stage of atherogenesis and can also be managed with appropriate treatment. This book describes the basics of hypercholesterolemia and its causes and various experimental animal models to understand and study the pathophysiology of hypercholesterolemia as well as to present practice-based clinical approaches to treat hypercholesterolemia. Further, the book describes various treatment strategies of hypercholesterolemia in detail, especially the appropriate use of statin. It is well known that the use of statin is an ideal as well as a potent therapy to lower cholesterol level and also has various beneficial pharmacological effects to prevent cardiovascular diseases. However, there exists less awareness about the use of statin. Hence, it is important to understand the appropriate use of statin in terms of doses for different stages of hypercholesterolemia, side effects, resistance of its use, and also interaction of statin with other drugs, which are well described in this book. In short, the major aim of this compendium is to present to the readers comprehensive, updated, and current research perspectives on hypercholesterolemia.

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HypercholesterolemiaEdited by Sekar Ashok Kumar

Published: September 17th 2015

DOI: 10.5772/58487

ISBN: 978-953-51-2169-5

eBook (PDF) ISBN: 978-953-51-7256-7

Copyright year: 2015

Books open for chapter submissions

18972 Total Chapter Downloads

20 Crossref Citations

25 Web of Science Citations

40 Dimensions Citations


Open access peer-reviewed

1. Animal Models of Diet-induced Hypercholesterolemia

By Jeannie Chan, Genesio M. Karere, Laura A. Cox and John L. VandeBerg


Open access peer-reviewed

2. Hypercholesterolemia in Childhood

By Lorenzo Iughetti, Barbara Predieri and Patrizia Bruzzi


Open access peer-reviewed

3. Role of Oxidized LDL in Atherosclerosis

By E. Leiva, S. Wehinger, L. Guzmán and R. Orrego


Open access peer-reviewed

4. A Practical Case- Based Approach to Dyslipidaemia in Light of the European Guidelines

By Olivier S. Descamps , Lale Tokgozoglu and Eric Bruckert


Open access peer-reviewed

5. Hypercholesterolemia Effect on Potassium Channels

By Anna N. Bukiya and Avia Rosenhouse-Dantsker


Open access peer-reviewed

6. Hypercholesterolemia as a Risk Factor for Catheterization- Related Cerebral Infarction — A Literature Review and a Summary of Cases

By Yusuke Morita, Takao Kato and Moriaki Inoko


Open access peer-reviewed

7. Medicinal Values of Selected Mushrooms with Special Reference to Anti-Hypercholesterolemia

By Choong Yew Keong


Open access peer-reviewed

8. Hypercholesterolemia — Statin Therapy — Indications, Side Effects, Common Mistakes in Handling, Last Evidence and Recommendations in Current Clinical Practice

By Lucía Cid-Conde and José López-Castro


Open access peer-reviewed

9. Pleiotropic Effects of Statins

By Sigrid Mennickent


Open access peer-reviewed

10. Resistance of Statin Therapy, and Methods for its Influence

By Lyudmila Georgieva Vladimirova-Kitova and Spas Ivanov Kitov


Open access peer-reviewed

11. Interaction Studies of ACE Inhibitors with Statins

By Safila Naveed


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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