Open access peer-reviewed Edited Volume

HIV-Host Interactions

HIV remains the major global health threat, and neither vaccine nor cure is available. Increasing our knowledge on HIV infection will help overcome the challenge of HIV/AIDS. This book covers several aspects of HIV-host interactions in vitro and in vivo. The first section covers the interaction between cellular components and HIV proteins, Integrase, Tat, and Nef. It also discusses the clinical relevance of HIV superinfection. The next two chapters focus on the role of innate immunity including dendritic cells and defensins in HIV infection followed by the section on the impact of host factors on HIV pathogenesis. The section of co-infection includes the impact of Human herpesvirus 6 and Trichomonas vaginalis on HIV infection. The final section focuses on generation of HIV molecular clones that can be used in macaques and the potential use of cotton rats for HIV studies.

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HIV-Host InteractionsEdited by Theresa Li-Yun Chang

Published: November 2nd 2011

DOI: 10.5772/808

ISBN: 978-953-307-442-9

eBook (PDF) ISBN: 978-953-51-6542-2

Copyright year: 2011

Books open for chapter submissions

31436 Total Chapter Downloads

9 Crossref Citations

25 Web of Science Citations

22 Dimensions Citations


Open access peer-reviewed

1. Molecular Crosstalk between HIV-1 Integration and Host Proteins – Implications for Therapeutics

By Youichi Suzuki, Yasutsugu Suzuki and Naoki Yamamoto


Open access peer-reviewed

2. HIV Infection «HIV Tat Protein, a Key Factor in Pathogenesis and Immune System Dysregulation: Implication of IL-10»

By Ben Haij N., Planès R., Mzoughi O. and Bahraoui E.


Open access peer-reviewed

3. HIV-1 Nef Transfer and Intracellular Signalling in Uninfected Cells

By Zulema A. Percario, Giorgio Mangino, Valentina Gallo, Maria Vincenza Chiantore, Gianna Fiorucci, Giovanna Romeo and Elisabetta Affabris


Open access peer-reviewed

4. Clinical Relevance of HIV-1 Superinfection

By Daniëlle Hoogmoed, Marion Cornelissen and Antoinette van der Kuyl


Open access peer-reviewed

5. Innate Immune Responses in HIV-Infection

By Wilfried Posch, Cornelia Lass-Flörl and Doris Wilflingseder


Open access peer-reviewed

6. Human Defensins in HIV Infection: Friends or Foes?

By Rachna Shah and Theresa L. Chang


Open access peer-reviewed

7. Factors Contributing to HIV-1 Induced Pathogenesis in the Human Thymus

By Bianca Blom, Marta Epeldegui and Christel H. Uittenbogaart


Open access peer-reviewed

8. Impact of HIV Infection and HAART Therapy on CD4 T Helper Cell Subset Expression and Function

By Christina Guzzo, Nor Fazila Che Mat, Xiubo Zhang and Katrina Gee


Open access peer-reviewed

9. Genetic Factors that Influence HIV Infection: The Role of the Major Histocompatibility Complex System

By Daniel Pérez-Núñez and Narcisa Martínez-Quiles


Open access peer-reviewed

10. Interactions of Infectious HIV-1 Virions with Erythrocytes: Implications for HIV-1 Pathogenesis and Infectivity

By Zoltan Beck and Carl R Alving


Open access peer-reviewed

11. In Vitro and In Vivo Transactivation of HIV-1 by Human Herpesvirus 6

By Ongrádi Joseph, Kövesdi Valéria, Nagy Károly, Matteoli Barbara, Ceccherini-Nelli Luca and Ablashi Dharam


Open access peer-reviewed

12. Inducing Immune Protection Against Trichomonas vaginalis: A Novel Vaccine Approach to Prevent HIV Transmission

By Sarah Cudmore, Jeffrey Smith and Gary Garber


Open access peer-reviewed

13. Macaque-Tropic HIV-1 Derivatives: A Novel Experimental Approach to Understand Viral Replication and Evolution in Vivo

By Masako Nomaguchi, Naoya Doi, Sachi Fujiwara and Akio Adachi


Open access peer-reviewed

14. The Quest for a Small Animal Model for HIV Infection and Disease

By Jorge C.G. Blanco, Lioubov M. Pletneva, Lorraine E. Earle and William I. Frels


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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