Open access peer-reviewed Edited Volume


Trends and Methodologies

Bioinformatics - Trends and Methodologies is a collection of different views on most recent topics and basic concepts in bioinformatics. This book suits young researchers who seek basic fundamentals of bioinformatic skills such as data mining, data integration, sequence analysis and gene expression analysis as well as scientists who are interested in current research in computational biology and bioinformatics including next generation sequencing, transcriptional analysis and drug design. Because of the rapid development of new technologies in molecular biology, new bioinformatic techniques emerge accordingly to keep the pace of in silico development of life science. This book focuses partly on such new techniques and their applications in biomedical science. These techniques maybe useful in identification of some diseases and cellular disorders and narrow down the number of experiments required for medical diagnostic.

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BioinformaticsTrends and MethodologiesEdited by Mahmood A. Mahdavi

Published: November 2nd 2011

DOI: 10.5772/786

ISBN: 978-953-307-282-1

eBook (PDF) ISBN: 978-953-51-5549-2

Copyright year: 2011

Books open for chapter submissions

78698 Total Chapter Downloads

43 Crossref Citations

61 Web of Science Citations

103 Dimensions Citations


Open access peer-reviewed

1. Concepts, Historical Milestones and the Central Place of Bioinformatics in Modern Biology: A European Perspective

By T.K. Attwood, A. Gisel, N-E. Eriksson and E. Bongcam-Rudloff


Open access peer-reviewed

2. Data Integration in Bioinformatics: Current Efforts and Challenges

By Zhang Zhang, Vladimir B. Bajic, Jun Yu, Kei-Hoi Cheung and Jeffrey P. Townsend


Open access peer-reviewed

3. Semantic Data Integration on Biomedical Data Using Semantic Web Technologies

By Roland Kienast and Christian Baumgartner


Open access peer-reviewed

4. Vector Space Information Retrieval Techniques for Bioinformatics Data Mining

By Eric Sakk and Iyanuoluwa E. Odebode


Open access peer-reviewed

5. Massively Parallelized DNA Motif Search on FPGA

By Yasmeen Farouk, Tarek ElDeeb and Hossam Faheem


Open access peer-reviewed

6. A Pattern Search Method for Discovering Conserved Motifs in Bioactive Peptide Families

By Feng Liu, Liliane Schoofs, Geert Baggerman, Geert Wets and Marleen Lindemans


Open access peer-reviewed

7. Database Mining: Defining the Pathogenesis of Inflammatory and Immunological Diseases

By Fan Yang, Irene Hwa Yang, Hong Wang and Xiao-Feng Yang


Open access peer-reviewed

8. Data Mining Pubmed Identifies Core Signalings and miRNA Regulatory Module in Glioma

By Chunsheng Kang, Junxia Zhang, Yingyi Wang, Ning Liu, Jilong Liu, Huazong Zeng, Tao Jiang, Yongping You and Peiyu Pu


Open access peer-reviewed

9. Significance Score of Motifs in Biological Sequences

By Grégory Nuel


Open access peer-reviewed

10. A Systematic and Thorough Search for Domains of the Scavenger Receptor Cysteine-Rich Group-B Family in the Human Genome

By Alexandre M. Carmo and Vattipally B. Sreenu


Open access peer-reviewed

11. Assessing Multiple Sequence Alignments Using Visual Tools

By Catherine L. Anderson, Cory L. Strope and Etsuko N. Moriyama


Open access peer-reviewed

12. Optimal Sequence Alignment and Its Relationship with Phylogeny

By Atoosa Ghahremani and Mahmood A. Mahdavi


Open access peer-reviewed

13. Predicting Virus Evolution

By Tom Burr


Open access peer-reviewed

14. A Bioinformatical Approach to Study the Endosomal Sorting Complex Required for Transport (ESCRT) Machinery in Protozoan Parasites: The Entamoeba histolytica Case

By Israel López-Reyes, Cecilia Bañuelos, Abigail Betanzos and Esther Orozco


Open access peer-reviewed

15. Structural Bioinformatics Analysis of Acid Alpha-Glucosidase Mutants with Pharmacological Chaperones

By Sheau Ling Ho


Open access peer-reviewed

16. Bioinformatics Domain Structure Prediction and Homology Modeling of Human Ryanodine Receptor 2

By V. Bauerová-Hlinková, J. Bauer, E. Hostinová, J. Gašperík, K. Beck, Ľ. Borko, A. Faltínová, A. Zahradníková and J. Ševčík


Open access peer-reviewed

17. Identifying Enzyme Knockout Strategies on Multiple Enzyme Associations

By Bin Song, I. Esra Büyüktahtakın, Nirmalya Bandyopadhyay, Sanjay Ranka and Tamer Kahveci


Open access peer-reviewed

18. Using Bacterial Artificial Chromosomes to Refine Genome Assemblies and to Build Virtual Genomes

By Abhirami Ratnakumar, Wesley Barris, Sean McWilliam and Brian P. Dalrymple


Open access peer-reviewed

19. Basidiomycetes Telomeres – A Bioinformatics Approach

By Lucía Ramírez, Gúmer Pérez, Raúl Castanera, Francisco Santoyo and Antonio G. Pisabarro


Open access peer-reviewed

20. SNPpattern: A Genetic Tool to Derive Haplotype Blocks and Measure Genomic Diversity in Populations Using SNP Genotypes

By Stephen J. Goodswen and Haja N. Kadarmideen


Open access peer-reviewed

21. Algorithms for CpG Islands Search: New Advantages and Old Problems

By Yulia A. Medvedeva


Open access peer-reviewed

22. Translational Oncogenomics and Human Cancer Interactomics: Advanced Techniques and Complex System Dynamic Approaches

By I. C. Baianu


Open access peer-reviewed

23. In-silico Approaches for RNAi Post-Transcriptional Gene Regulation: Optimizing siRNA Design and Selection

By Mahmoud ElHefnawi and Mohamed Mysara


Open access peer-reviewed

24. MicroRNA Targeting in Heart: A Theoretical Analysis

By Zhiguo Wang


Open access peer-reviewed

25. Genome-Wide Identification of Estrogen Receptor Alpha Regulated miRNAs Using Transcription Factor Binding Data

By Jianzhen Xu, Xi Zhou and Chi-Wai Wong


Open access peer-reviewed

26. Quantification of Gene Expression Based on Microarray Experiment

By Samane F. Farsani and Mahmood A. Mahdavi


Open access peer-reviewed

27. On-Chip Living-Cell Microarrays for Network Biology

By Ronnie Willaert and Hichem Sahli


Open access peer-reviewed

28. Novel Machine Learning Techniques for Micro-Array Data Classification

By Neamat El Gayar, Eman Ahmed and Iman El Azab


Open access peer-reviewed

29. Deep Sequencing Data Analysis: Challenges and Solutions

By Ofer Isakov and Noam Shomron


Open access peer-reviewed

30. Whole Genome Annotation: In Silico Analysis

By Vasco Azevedo, Vinicius Abreu, Sintia Almeida, Anderson Santos, Siomar Soares, Amjad Ali, Anne Pinto, Aryane Magalhães, Eudes Barbosa, Rommel Ramos, Louise Cerdeira, Adriana Carneiro, Paula Schneider, Artur Silva and Anderson Miyoshi


Open access peer-reviewed

31. Designing of Anti-Cancer Drug Targeted to Bcl-2 Associated Athanogene (BAG1) Protein

By Amit Kumar, Kriti Verma and Amita Sinha


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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