Open access peer-reviewed Edited Volume

DNA Methylation

From Genomics to Technology

Edited by Tatiana Tatarinova

University of Southern California, United States of America

Epigenetics is one of the most exciting and rapidly developing areas of modern genetics with applications in many disciplines from medicine to agriculture. The most common form of epigenetic modification is DNA methylation, which plays a key role in fundamental developmental processes such as embryogenesis and also in the response of organisms to a wide range of environmental stimuli. Indeed, epigenetics is increasing regarded as one of the major mechanisms used by animals and plants to modulate their genome and its expression to adapt to a wide range of environmental factors. This book brings together a group of experts at the cutting edge of research into DNA methylation and highlights recent advances in methodology and knowledge of underlying mechanisms of this most important of genetic processes. The reader will gain an understanding of the impact, significance and recent advances within the field of epigenetics with a focus on DNA methylation.

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DNA MethylationFrom Genomics to TechnologyEdited by Tatiana Tatarinova

Published: March 16th 2012

DOI: 10.5772/2159

ISBN: 978-953-51-0320-2

eBook (PDF) ISBN: 978-953-51-5244-6

Copyright year: 2012

Books open for chapter submissions

46313 Total Chapter Downloads

18 Crossref Citations

27 Web of Science Citations

36 Dimensions Citations


Open access peer-reviewed

1. Modelling DNA Methylation Dynamics

By Karthika Raghavan and Heather J. Ruskin


Open access peer-reviewed

2. DNA Methylation Profiling from High-Throughput Sequencing Data

By Michael Hackenberg, Guillermo Barturen and José L. Oliver


Open access peer-reviewed

3. GC3 Biology in Eukaryotes and Prokaryotes

By Eran Elhaik and Tatiana Tatarinova


Open access peer-reviewed

4. Inheritance of DNA Methylation in Plant Genome

By Tomoko Takamiya, Saeko Hosobuchi, Kaliyamoorthy Seetharam, Yasufumi Murakami and Hisato Okuizumi


Open access peer-reviewed

5. MethylMeter(r): A Quantitative, Sensitive, and Bisulfite-Free Method for Analysis of DNA Methylation

By David R. McCarthy, Philip D. Cotter, and Michelle M. Hanna


Open access peer-reviewed

6. DNA Methylation in Mammalian and Non-Mammalian Organisms

By Michael Moffat, James P. Reddington, Sari Pennings and Richard R. Meehan


Open access peer-reviewed

7. Could Tissue-Specific Genes be Silenced in Cattle Carrying the Rob(1;29) Robertsonian Translocation?

By Alicia Postiglioni, Rody Artigas, Andrés Iriarte, Wanda Iriarte, Nicolás Grasso and Gonzalo Rincón


Open access peer-reviewed

8. Epigenetic Defects Related Reproductive Technologies: Large Offspring Syndrome (LOS)

By Makoto Nagai, Makiko Meguro-Horike and Shin-ichi Horike


Open access peer-reviewed

9. Aberrant DNA Methylation of Imprinted Loci in Male and Female Germ Cells of Infertile Couples

By Takahiro Arima, Hiroaki Okae, Hitoshi Hiura, Naoko Miyauchi, Fumi Sato, Akiko Sato and Chika Hayashi


Open access peer-reviewed

10. DNA Methylation and Trinucleotide Repeat Expansion Diseases

By Mark A. Pook


Open access peer-reviewed

11. Investigating the Role DNA Methylations Plays in Developing Hepatocellular Carcinoma Associated with Tyrosinemia Type 1 Using the Comet Assay

By Johannes F. Wentzel and Pieter J. Pretorius


Open access peer-reviewed

12. DNA Methylation and Histone Deacetylation: Interplay and Combined Therapy in Cancer

By Yi Qiu, Daniel Shabashvili, Xuehui Li, Priya K. Gopalan, Min Chen and Maria Zajac-Kaye


Open access peer-reviewed

13. Effects of Dietary Nutrients on DNA Methylation and Imprinting

By Ali A. Alshatwi and Gowhar Shafi


Open access peer-reviewed

14. Epigenetic Alteration of Receptor Tyrosine Kinases in Cancer

By Anica Dricu, Stefana Oana Purcaru, Raluca Budiu, Roxana Ola, Daniela Elise Tache, Anda Vlad


Open access peer-reviewed

15. The Importance of Aberrant DNA Methylation in Cancer

By Koraljka Gall Trošelj, Renata Novak Kujundžić and Ivana Grbeša


Open access peer-reviewed

16. DNA Methylation in Acute Leukemia

By Kristen H. Taylor and Michael X. Wang


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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