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Open access peer-reviewed Edited Volume

Readings in Advanced Pharmacokinetics

Theory, Methods and Applications

This book, “Readings in Advanced Pharmacokinetics - Theory, Methods and Applications”, covers up to date information and practical topics related to the study of drug pharmacokinetics in humans and in animals. The book is designed to offer scientists, clinicians and researchers a choice to logically build their knowledge in pharmacokinetics from basic concepts to advanced applications. This book is organized into two sections. The first section discusses advanced theories that include a wide range of topics; from bioequivalence studies, pharmacogenomics in relation to pharmacokinetics, computer based simulation concepts to drug interactions of herbal medicines and veterinary pharmacokinetics. The second section advances theory to practice offering several examples of methods and applications in advanced pharmacokinetics.

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Readings in Advanced PharmacokineticsTheory, Methods and ApplicationsEdited by Ayman Noreddin

Published: April 20th 2012

DOI: 10.5772/1982

ISBN: 978-953-51-0533-6

eBook (PDF) ISBN: 978-953-51-6973-4

Copyright year: 2012

Books open for chapter submissions

100307 Total Chapter Downloads

17 Crossref Citations

38 Web of Science Citations

52 Dimensions Citations


Open access peer-reviewed

1. Bioequivalence Studies

By Aisha Qayyum


Open access peer-reviewed

2. Computer Simulations as a Tool for Optimizing Bioequivalence Trials

By Carmen Navarro-Fontestad,Victor Mangas-Sanjuán, Isabel González-Álvarez, Alfredo García-Arieta, Carlos Fernández-Teruel, Vicente G. Casabó-Alós and Marival Bermejo


Open access peer-reviewed

3. Evaluation of Percutaneous Drug Permeation Using a Lateral Sectioning Approach

By Nobuhiro Goi, Katsunori Morishita, Akihito Taniguchi and Takayuki Ishii


Open access peer-reviewed

4. Pharmacogenomics Dictate Pharmacokinetics: Polymorphisms in Drug-Metabolizing Enzymes and Drug-Transporters

By Debasis Mondal, Samantha L. Gerlach, Amrita Datta, Geetika Chakravarty and Asim B. Abdel-Mageed


Open access peer-reviewed

5. Genetic Variation in Drug Disposition

By Balmukunda Regmi and Laxman Bharati


Open access peer-reviewed

6. Application of Pharmacokinetics/Pharmacodynamics (PK/PD) in Designing Effective Antibiotic Treatment Regimens

By Ghada F. Ahmed and Ayman M. Noreddin


Open access peer-reviewed

7. Pharmacokinetics and Drug Interactions of Herbal Medicines: A Missing Critical Step in the Phytomedicine/Drug Development Process

By Obiageri O. Obodozie


Open access peer-reviewed

8. Pharmacokinetics of Antimicrobials in Food Producing Animals

By S. K. Bhavsar and A. M. Thaker


Open access peer-reviewed

9. Comparative Veterinary Pharmacokinetics

By Akos Jerzsele


Open access peer-reviewed

10. Observer-Based Strategies for Anesthesia Drug Concentration Estimation

By Jin-Oh Hahn, Guy A. Dumont and J. Mark Ansermino


Open access peer-reviewed

11. Optimal Pharmacokinetics of Cyclosporine and Tacrolimus Based Relationship Among AUC, Trough and Peak Concentration

By Hironori Takeuchi


Open access peer-reviewed

12. Pharmacokinetics and Metabolized Caroteniods in Liver of Single Dose Administration in Fancy Carp (Cyprinus carpio)

By Bundit Yuangsoi


Open access peer-reviewed

13. Correlation of in vitro Dissolution Profiles with in vivo Pharmacokinetic Parameters of Some Commercial Brands of Aspirin Tablets Marketed in Nigeria

By Emmanuel Adelaja Bamigbola


Open access peer-reviewed

14. Bioavailability of Citrus Polymethoxylated Flavones and Their Biological Role in Metabolic Syndrome and Hyperlipidemia

By Malkanthi Evans, Prachi Sharma and Najla Guthrie


Open access peer-reviewed

15. Role of Aldehyde Oxidase and Xanthine Oxidase in the Metabolism of Purine-Related Drugs

By Mohammad-Reza Rashidi and Roghiyeh Pashaei-Asl


Open access peer-reviewed

16. Pharmacokinetic/Pharmacodynamic (PK/PD) Modeling of Anti-Neoplastic Agents

By Daniel Lexcen, Ahmed Salem, Walid M. El-Khatib, Virginia Haynes and Ayman Noreddin


Open access peer-reviewed

17. Pharmacokinetic (PK) and Pharmacodynamic Profiles of Artemisinin Derivatives Influence Drug Neurotoxicity in Animals

By Qigui Li and Mark Hickman


Open access peer-reviewed

18. One Step Closer to the Target: Intracellular Pharmacokinetics of Gemcitabine

By Matthew Links and Peter Galettis


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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