Open access peer-reviewed Edited Volume


Role in Health and Diseases

Edited by Suman Kapur

Birla Institute of Technology and Science, Pilani, India


A need for a book on immunology which primarily focuses on the needs of medical and clinical research students was recognized. This book, "Immunosuppression - Role in Health and Diseases" is relatively short and contains topics relevant to the understanding of human immune system and its role in health and diseases. Immunosuppression involves an act that reduces the activation or efficacy of the immune system. Therapeutic immunosuppression has applications in clinical medicine, ranging from prevention and treatment of organ/bone marrow transplant rejection, management of autoimmune and inflammatory disorders. It brings important developments both in the field of molecular mechanisms involved and active therapeutic approaches employed for immunosuppression in various human disease conditions. There was a need to bring this information together in a single volume, as much of the recent developments are dispersed throughout biomedical literature, largely in specialized journals. This book will serve well the practicing physicians, surgeons and biomedical scientists as it provides an insight into various approaches to immunosuppression and reviews current developments in each area.

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ImmunosuppressionRole in Health and DiseasesEdited by Suman Kapur

Published: February 24th 2012

DOI: 10.5772/1897

ISBN: 978-953-51-0152-9

eBook (PDF) ISBN: 978-953-51-6849-2

Copyright year: 2012

Books open for chapter submissions

57605 Total Chapter Downloads

7 Crossref Citations

16 Web of Science Citations

20 Dimensions Citations


Open access peer-reviewed

1. Role of Opioidergic System in Humoral Immune Response

By Suman Kapur, Anuradha Pal and Shashwat Sharad


Open access peer-reviewed

2. Endotoxin Tolerance as a Key Mechanism for Immunosuppression

By Subhra K. Biswas and Irina N. Shalova


Open access peer-reviewed

3. Spleen Tyrosine Kinase: A Novel Target in Autoimmunity

By Stephen P. McAdoo and Frederick W. K. Tam


Open access peer-reviewed

4. Genetic Variation in AhR Gene Related to Dioxin Sensitivity in the Japanese Field Mouse, Apodemus speciosus

By Hiroko Ishiniwa, Kazuhiro Sogawa, Ken-ichi Yasumoto, Nobuhiko Hoshi, Toshifumi Yokoyama,Ken Tasaka and Tsuneo Sekijima


Open access peer-reviewed

5. Anti-RhD-Mediated Immunosuppression: Can Monoclonal Antibodies Imitate the Action of Polyclonal Antibodies?

By Natalia Olovnikova


Open access peer-reviewed

6. Immunotropic Properties of GABA-ergic Agents in Suppression

By N. Tyurenkov and M. A. Samotrueva


Open access peer-reviewed

7. Immunodepression and Immunosuppression During Aging

By Véronique Thomas-Vaslin, Adrien Six, Hang-Phuong Pham, Cira Dansokho, Wahiba Chaara, Bruno Gouritin, Bertrand Bellier and David Klatzmann


Open access peer-reviewed

8. Chronic Immune Response Hypothesis for Chronic Fatigue Syndrome: Experimental Results and Literature Overview

By E. V. Svirshchevskaya


Open access peer-reviewed

9. T Cell Suppression in Burn and Septic Injuries

By Nadeem Fazal


Open access peer-reviewed

10. Immunosuppression in Helminth Infection

By Maria Doligalska and Katarzyna Donskow-Łysoniewska


Open access peer-reviewed

11. Microbial Immunosuppression

By Mohamed G. Elfaki, Abdullah A. Al-Hokail and Abdelmageed M. Kambal


Open access peer-reviewed

12. Measles Virus Infection: Mechanisms of Immune Suppression

By Xuelian Yu and Reena Ghildyal


Open access peer-reviewed

13. Immunoregulation: A Proposal for an Experimental Model

By Marcela Šperanda and Ivica Valpotić


Open access peer-reviewed

14. Cellular Therapies for Immunosuppression

By Nathalie Cools, Viggo F. I. Van Tendeloo and Zwi N. Berneman


Open access peer-reviewed

15. Low Immunogenic Potential of Human Neural Stem Cells

By L. De Filippis, L. Rota Nodari and Maurizio Gelati


Open access peer-reviewed

16. Current Immunosuppression in Abdominal Organ Transplantation

By Raffaele Girlanda, Cal S. Matsumoto, Keith J. Melancon and Thomas M. Fishbein


Open access peer-reviewed

17. Induction Therapy in Renal Transplant Recipients

By Cheguevara Afaneh, Meredith J. Aull, Sandip Kapur and David B. Leeser


Open access peer-reviewed

18. Radiotherapy and Immunity – A Mini Review

By Rosangela Correa Villar


Open access peer-reviewed

19. The Role of Cyclosporine A in the Treatment of Prosthetic Vascular Graft Infections with the Use of Arterial Homografts

By Artur Pupka and Tomasz Płonek


Open access peer-reviewed

20. Clinical Immunosuppression in Solid Organ and Composite Tissue Allotransplantation

By Barbara Kern and Robert Sucher


Open access peer-reviewed

21. HIV/AIDS Associated Malignant Disorders: Role of Highly Active Antiretroviral Therapy

By Angel Mayor, Yelitza Ruiz, Diana Fernández and Robert Hunter-Mellado


Open access peer-reviewed

22. E-Health 2.0 Developments in Treatment and Research in Multiple Sclerosis

By Peter Joseph Jongen


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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