Open access peer-reviewed Edited Volume

Advances in Precision Medicine Oncology

Edited by Hilal Arnouk

Midwestern University


Bassam Hassan

Al-Rafidain University College

Recent advances in precision medicine and immuno-oncology have led to highly specific and efficacious cancer therapies such as monoclonal antibodies and immune checkpoint inhibitors (ICIs). This book provides an up-to-date overview of advances in the field of immuno-oncology. Chapters cover such topics as ICIs and how they mount a robust immune response against cancer cells as well as the response of ICIs to treatment predictive biomarkers and their potential immune-related adverse events (irAEs). Additionally, the book includes a comprehensive review of the powerful FDA-approved therapeutic agent doxorubicin, highlighting the molecular mechanisms behind doxorubicin’s drug resistance and critical side effects.

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Advances in Precision Medicine OncologyEdited by Hilal Arnouk

Published: July 21st 2021

DOI: 10.5772/intechopen.91507

ISBN: 978-1-83968-868-3

Print ISBN: 978-1-83968-867-6

eBook (PDF) ISBN: 978-1-83968-869-0

Copyright year: 2021

Books open for chapter submissions

1358 Total Chapter Downloads


Open access peer-reviewed

1. Immune and Cell Cycle Checkpoint Inhibitors for Cancer Immunotherapy

By Erlinda M. Gordon, Nicole L. Angel, Ted T. Kim, Don A. Brigham, Sant P. Chawla and Frederick L. Hall


Open access peer-reviewed

2. Evolving Dynamic Biomarkers for Prediction of Immune Responses to Checkpoint Inhibitors in Cancer

By Afsheen Raza, Maysaloun Merhi, Allan Relecom, Queenie Fernandes, Varghese Inchakalody, Abdul Rahman Zar Gul, Shahab Uddin, Mohammed Ussama Al Homsi and Said Dermime


Open access peer-reviewed

3. The Endocrinological Side Effects of Immunotherapies

By Anush Patel, Haisam Abid and Amrat Kumar


Open access peer-reviewed

4. Immunotherapy in Malignant Pleural Mesothelioma

By Asako Matsuda and Nobukazu Fujimoto


Open access peer-reviewed

5. Targeted Cancer Therapy Using Nanoparticles and Antibody Fragments

By Sankha Bhattacharya and Kapil Gore


Open access peer-reviewed

6. Antibody Therapy Targeting Cancer-Specific Cell Surface Antigen AGR2

By Alvin Y. Liu, Tatjana Crnogorac-Jurcevic, James J. Lai and Hung-Ming Lam


Open access peer-reviewed

7. Advances in Adoptive Cellular Therapy (ACT)

By Rajesh Kumar Yadav, Bandana Kumari, Pritanjali Singh, Asgar Ali, Sadhana Sharma and Krishnan Hajela


Open access peer-reviewed

8. Mathematical Modeling and Dynamics of Oncolytic Virotherapy

By Abdullah Abu-Rqayiq


Open access peer-reviewed

9. Molecular-Level Understanding of the Anticancer Action Mechanism of Anthracyclines

By Manish Shandilya, Shrutika Sharma, Prabhu Prasad Das and Sonika Charak


Open access peer-reviewed

10. Overview on the Side Effects of Doxorubicin

By Chittipolu Ajaykumar


Open access peer-reviewed

11. Overcoming P-Glycoprotein-Mediated Doxorubicin Resistance

By Suree Jianmongkol


Open access peer-reviewed

12. Improving the Antitumor Effect of Doxorubicin in the Treatment of Eyeball and Orbital Tumors

By Anatoliy Parfentievich Maletskyy, Yuriy Markovich Samchenko and Natalia Mikhailivna Bigun


Open access peer-reviewed

13. The Paradigm of Targeting an Oncogenic Tyrosine Kinase: Lesson from BCR-ABL

By Enrico Bracco, M. Shahzad Ali, Stefano Magnati and Giuseppe Saglio


Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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