Open access peer-reviewed Edited Volume

Advances in Precision Medicine Oncology

Edited by Hilal Arnouk

Midwestern University

Co-editor:

Bassam Hassan

Al-Rafidain University College

Recent advances in precision medicine and immuno-oncology have led to highly specific and efficacious cancer therapies such as monoclonal antibodies and immune checkpoint inhibitors (ICIs). This book provides an up-to-date overview of advances in the field of immuno-oncology. Chapters cover such topics as ICIs and how they mount a robust immune response against cancer cells as well as the response of ICIs to treatment predictive biomarkers and their potential immune-related adverse events (irAEs). Additionally, the book includes a comprehensive review of the powerful FDA-approved therapeutic agent doxorubicin, highlighting the molecular mechanisms behind doxorubicin’s drug resistance and critical side effects.

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Advances in Precision Medicine OncologyEdited by Hilal Arnouk

Published: July 21st 2021

DOI: 10.5772/intechopen.91507

ISBN: 978-1-83968-868-3

Print ISBN: 978-1-83968-867-6

eBook (PDF) ISBN: 978-1-83968-869-0

Copyright year: 2021

Books open for chapter submissions

1358 Total Chapter Downloads

chaptersDownloads

Open access peer-reviewed

1. Immune and Cell Cycle Checkpoint Inhibitors for Cancer Immunotherapy

By Erlinda M. Gordon, Nicole L. Angel, Ted T. Kim, Don A. Brigham, Sant P. Chawla and Frederick L. Hall

86

Open access peer-reviewed

2. Evolving Dynamic Biomarkers for Prediction of Immune Responses to Checkpoint Inhibitors in Cancer

By Afsheen Raza, Maysaloun Merhi, Allan Relecom, Queenie Fernandes, Varghese Inchakalody, Abdul Rahman Zar Gul, Shahab Uddin, Mohammed Ussama Al Homsi and Said Dermime

111

Open access peer-reviewed

3. The Endocrinological Side Effects of Immunotherapies

By Anush Patel, Haisam Abid and Amrat Kumar

57

Open access peer-reviewed

4. Immunotherapy in Malignant Pleural Mesothelioma

By Asako Matsuda and Nobukazu Fujimoto

115

Open access peer-reviewed

5. Targeted Cancer Therapy Using Nanoparticles and Antibody Fragments

By Sankha Bhattacharya and Kapil Gore

96

Open access peer-reviewed

6. Antibody Therapy Targeting Cancer-Specific Cell Surface Antigen AGR2

By Alvin Y. Liu, Tatjana Crnogorac-Jurcevic, James J. Lai and Hung-Ming Lam

85

Open access peer-reviewed

7. Advances in Adoptive Cellular Therapy (ACT)

By Rajesh Kumar Yadav, Bandana Kumari, Pritanjali Singh, Asgar Ali, Sadhana Sharma and Krishnan Hajela

46

Open access peer-reviewed

8. Mathematical Modeling and Dynamics of Oncolytic Virotherapy

By Abdullah Abu-Rqayiq

55

Open access peer-reviewed

9. Molecular-Level Understanding of the Anticancer Action Mechanism of Anthracyclines

By Manish Shandilya, Shrutika Sharma, Prabhu Prasad Das and Sonika Charak

252

Open access peer-reviewed

10. Overview on the Side Effects of Doxorubicin

By Chittipolu Ajaykumar

167

Open access peer-reviewed

11. Overcoming P-Glycoprotein-Mediated Doxorubicin Resistance

By Suree Jianmongkol

163

Open access peer-reviewed

12. Improving the Antitumor Effect of Doxorubicin in the Treatment of Eyeball and Orbital Tumors

By Anatoliy Parfentievich Maletskyy, Yuriy Markovich Samchenko and Natalia Mikhailivna Bigun

59

Open access peer-reviewed

13. The Paradigm of Targeting an Oncogenic Tyrosine Kinase: Lesson from BCR-ABL

By Enrico Bracco, M. Shahzad Ali, Stefano Magnati and Giuseppe Saglio

66

Edited Volume and chapters are indexed in

  • Worldcat
  • OpenAIRE
  • Google Scholar
  • AZ ebsco
  • Base
  • CNKI

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