Prof. Andrea Tranquilli
Università Politecnica Marche, Italy
Thrombophilia(s) is a condition of increased tendency to form blood clots. This condition may be inherited or acquired, and this is why the term is often used in plural. People who have thrombophilia are at greater risk of having thromboembolic complications, such as deep venous thrombosis, pulmonary embolism or cardiovascular complications, like stroke or myocardial infarction, nevertheless those complications are rare and it is possible that those individuals will never encounter clotting problems in their whole life. The enhanced blood coagulability is exacerbated under conditions of prolonged immobility, surgical interventions and most of all during pregnancy and puerperium, and the use of estrogen contraception. This is the reason why many obstetricians-gynecologysts became involved in this field aside the hematologists: women are more frequently at risk. The availability of new lab tests for hereditary thrombophilia(s) has opened a new era with reflections on epidemiology, primary healthcare, prevention and prophylaxis, so that thrombophilia is one of the hottest topics in contemporary medicine.
Hypothyroidism, Fertility and Pregnancy
in the book "Current Topics in Hypothyroidism with Focus on Development" edited by Eliška Potluková, ISBN 978-953-51-0970-9, InTech, February 2, 2013
in the book "Thrombophilia" edited by Andrea Luigi Tranquilli, ISBN 978-953-307-872-4, InTech, November 11, 2011