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This book is indexed in
Medicine » Medical Genetics
Viral Gene Therapy
Edited by Ke Xu, ISBN 978-953-307-539-6, Hard cover, 450 pages, Publisher: InTech, Chapters published July 20, 2011 under CC BY-NC-SA 3.0 license
DOI: 10.5772/1011 
The development of technologies that allow targeting of specific cells has progressed substantially in recent years for several types of vectors, particularly viral vectors, which have been used in 70% of gene therapy clinical trials. Particular viruses have been selected as gene delivery vehicles because of their capacities to carry foreign genes and their ability to efficiently deliver these genes associated with efficient gene expression. This book is designed to present the most recent advances in viral gene therapy
- Chapter 1
Retroviral Vectors in Gene Therapy: Mechanism of Integration, Successes in Gene Therapy Trials, Emerging Problems and Potential Solutions - Chapter 2 Production of Retroviral and Lentiviral Gene Therapy Vectors: Challenges in the Manufacturing of Lipid Enveloped Virus
- Chapter 3 Surface Modification of Retroviral Vectors for Gene Therapy
- Chapter 4 The Glucocorticoid Receptor in Retroviral Infection
- Chapter 5 Adenoviral Vectors: Potential and Challenges as a Gene Delivery System
- Chapter 6 Adenovirus-Based Gene Therapy for Cancer
- Chapter 7 Recombinant Adenovirus Vector Infection of Human Dendritic Cells
- Chapter 8 Harnessing the Potential of Adenovirus Vectored Vaccines
- Chapter 9 Adeno Associated Virus Mediated β-Thalassemia Gene Therapy
- Chapter 10 Comparison of AAV Serotypes for Gene Delivery to Dopaminergic Neurons in the Substantia Nigra
- Chapter 11 Progress and Challenges in AAV-Mediated Gene Therapy for Duchenne Muscular Dystrophy
- Chapter 12 Viral Vectors as Tools to Investigate the Role of Dysregulated Proteins in Nervous System Pathologies: the Case of Acquired Motor Neuropathies
- Chapter 13 Designing Lentiviral Gene Vectors
- Chapter 14 Gene Regulatable Lentiviral Vector System
- Chapter 15 Dendritic Cells and Lentiviral Vectors: Mapping the Way to Successful Immuno Gene Therapy
- Chapter 16 Development and Application of HIV Vectors Pseudotyped with HIV Envelopes
- Chapter 17 Highly Efficient Retrograde Gene Transfer for Genetic Treatment of Neurological Diseases
- Chapter 18 Herpes Simplex Type 1 for Use in Cancer Gene Therapy: Looking Backward to Move Forward
- Chapter 19 Gene Therapy of Melanoma Using Inactivated Sendai Virus Envelope Vector (HVJ-E) with Intrinsic Anti-Tumor Activities
- Chapter 20 Pharmacokinetic Study of Viral Vectors for Gene Therapy: Progress and Challenges