Medicine » Cardiology and Cardiovascular Medicine

Recent Advances in Infective Endocarditis

Edited by Steven W. Kerrigan, ISBN 978-953-51-1169-6, 132 pages, Publisher: InTech, Chapters published June 27, 2013 under CC BY 3.0 license
DOI: 10.5772/46221
Edited Volume

Endocarditis is an inflammation of the lining of the heart and valves. It can be due to a non-infectious cause but when the inflammation is associated with an infection, usually bacterial, it is known as infective endocarditis. It is typically characterized by the development of a large septic thrombus on one of the cardiac valves. As this thrombus grows, it can lead to valve failure or may fragment forming a septic embolus that is associated with high mortality if the target of the embolus is the brain, heart or lung. This book reviews multi-organ complications associated with Infective endocarditis including significant recent advances in molecular mechanisms underlying thrombus formation on the cardiac valve, anti-microbial treatment and surgery.