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Ovarian Cancer - Basic Science Perspective
Edited by Samir A. Farghaly, ISBN 978-953-307-812-0, Hard cover, 406 pages, Publisher: InTech, Published: February 17, 2012 under CC BY 3.0 license, in subject Obstetrics and Gynecology
DOI: 10.5772/1268
Worldwide, Ovarian carcinoma continues to be responsible for more deaths than all other gynecologic malignancies combined. International leaders in the field address the critical biologic and basic science issues relevant to the disease. The book details the molecular biological aspects of ovarian cancer. It provides molecular biology techniques of understanding this cancer. The techniques are designed to determine tumor genetics, expression, and protein function, and to elucidate the genetic mechanisms by which gene and immunotherapies may be perfected. It provides an analysis of current research into aspects of malignant transformation, growth control, and metastasis. A comprehensive spectrum of topics is covered providing up to date information on scientific discoveries and management considerations.
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Book contents
- Chapter 1Oncogenic Pathway Signatures and Survival Outcome
- Chapter 2Epidemiology and Etiology of Ovarian Cancer
- Chapter 3Inflammation and Ovarian Cancer
- Chapter 4Photonic Sensor System for Screening Serum Biomarker Proteins in Ovarian Cancer
- Chapter 5The Role of MUC16 Mucin (CA125) in the Pathogenesis of Ovarian Cancer
- Chapter 6Apoptosis Pathways in Ovarian Cancer
- Chapter 7Dysregulated TGFB Signaling in Ovarian Cancer
- Chapter 8New Tumor Biomarkers in Ovarian Cancer and Its Prognostic and Clinical Relevance
- Chapter 9Sensitive Detection of Epithelial Ovarian Cancer Biomarkers Using Tag-Laser Induced Breakdown Spectroscopy
- Chapter 10Homeobox Genes and Their Functional Significance in Ovarian Tumorigenesis
- Chapter 11Transcriptomic Analysis of Human Ovarian Cancer Cells: Changes Mediated by Luteinizing Hormone Receptor Activation
- Chapter 12Potential Tumor Biomarkers for Ovarian Cancer
- Chapter 13Ectoenzymes in Epithelial Ovarian Carcinoma: Potential Diagnostic Markers and Therapeutic Targets
- Chapter 14P53 Network in Ovarian Cancer
- Chapter 15Gene Amplification in Ovarian Carcinomas: Lessons from Selected Amplified Gene Families
- Chapter 16Nitric Oxide/Protein Kinase G-Iα Promotes c-Src Activation, Proliferation and Chemoresistance in Ovarian Cancer
- Chapter 17VEGF Targeting Agents in Ovarian Cancer
- Chapter 18Autotaxin – A Target for the Treatment of Drug-Resistant Ovarian Cancer?
- Chapter 19Potential Monoclonal Antibody Therapy for the Treatment of Ovarian Cancer
