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This book is indexed in
Medicine » Medical Genetics
Non-Viral Gene Therapy
Edited by Xu-bo Yuan, ISBN 978-953-307-538-9, Hard cover, 696 pages, Publisher: InTech, Chapters published November 07, 2011 under CC BY 3.0 license
DOI: 10.5772/1010 
This book focuses on recent advancement of gene delivery systems research. With the multidisciplinary contribution in gene delivery, the book covers several aspects in the gene therapy development: various gene delivery systems, methods to enhance delivery, materials with modification and multifunction for the tumor or tissue targeting. This book will help molecular biologists gain a basic knowledge of gene delivery vehicles, while drug delivery scientist will better understand DNA, molecular biology, and DNA manipulation.
- Chapter 1
Non-Viral Gene Therapy Vectors Carrying Genomic Constructs - Chapter 2 Non-Viral Delivery Systems in Gene Therapy and Vaccine Development
- Chapter 3 Gene Delivery Systems: Tailoring Vectors to Reach Specific Tissues
- Chapter 4 Investigation of Transfection Barriers Involved in Non-Viral Nanoparticulate Gene Delivery in Different Cell Lines
- Chapter 5 The Mechanical Agitation Method of Gene Transfer for Ex-Vivo Gene Therapy
- Chapter 6 Gene Therapy of Some Genetic Diseases by Transferring Normal Human Genomic DNA into Somatic Cells and Stem Cells from Patients
- Chapter 7 Non Viral Gene Transfer Approaches for Lysosomal Storage Disorders
- Chapter 8 DNA Vaccination by Electrogene Transfer
- Chapter 9 Gene Delivery with Ultrasound and Microbubbles
- Chapter 10 Ultrasound-Mediated Gene Delivery
- Chapter 11 Polyamine – Lipid Conjugates as Effective Gene Carriers: Chemical Structure, Morphology, and Gene Transfer Activity
- Chapter 12 Technological Aspects of Scalable Processes for the Production of Functional Liposomes for Gene Therapy
- Chapter 13 Cationic Liposomes in Different Structural Levels for Gene Delivery
- Chapter 14 Neutral Liposomes and DNA Transfection
- Chapter 15 Non-Viral Gene Delivery Systems Based on Cholesterol Cationic Lipids: Structure-Activity Relationships
- Chapter 16 Polycation-Mediated Gene Delivery: The Physicochemical Aspects Governing the Process
- Chapter 17 Medical Polymer-Based Gene Therapy
- Chapter 18 Chitosan and Its Modifications: Are They Possible Vehicles for Gene Therapy?
- Chapter 19 Chitosan-DNA/siRNA Nanoparticles for Gene Therapy
- Chapter 20 Toxicity of Polymeric-Based Non-Viral Vector Systems for Pulmonary siRNA Application
- Chapter 21 PAMAM Dendrimer as Potential Delivery System for Combined Chemotherapeutic and MicroRNA-21 Gene Therapy
- Chapter 22 Nanomedicine Based Approaches to Cancer Diagonsis and Therapy
- Chapter 23 Toxicogenomics of Nonviral Cationic Gene Delivery Nanosystems
- Chapter 24 Nano-Particulate Calcium Phosphate as a Gene Delivery System
- Chapter 25 Modular Multifunctional Protein Vectors for Gene Therapy
- Chapter 26 Peptides as Promising Non-Viral Vectors for Gene Therapy
- Chapter 27 Binding of Protein-Functionalized Entities onto Synthetic Vesicles
- Chapter 28 Targeting TRAIL Receptors with Genetically- Engineered CD34+ Hematopoietic Stem Cells
- Chapter 29 Pyrrole-Imidazole Polyamides for Gene Therapy: Bioanalytical Methods and Pharmacokinetics