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Neural Stem Cells and Therapy
Edited by Tao Sun, ISBN 978-953-307-958-5, Hard cover, 440 pages, Publisher: InTech, Published: February 15, 2012 under CC BY 3.0 license, in subject Stem Cell Research
DOI: 10.5772/1250
This book is a collective work of international experts in the neural stem cell field. The book incorporates the characterization of embryonic and adult neural stem cells in both invertebrates and vertebrates. It highlights the history and the most advanced discoveries in neural stem cells, and summarizes the mechanisms of neural stem cell development. In particular, this book provides strategies and discusses the challenges of utilizing neural stem cells for therapy of neurological disorders and brain and spinal cord injuries. It is suitable for general readers, students, doctors and researchers who are interested in understanding the principles of and new discoveries in neural stem cells and therapy.
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Book contents
- Chapter 1Neural Stem Cells from Mammalian Brain: Isolation Protocols and Maintenance Conditions
- Chapter 2Neurogenesis in Adult Hippocampus
- Chapter 3Cellular Organization of the Subventricular Zone in the Adult Human Brain: A Niche of Neural Stem Cells
- Chapter 4The Spinal Cord Neural Stem Cell Niche
- Chapter 5Development of New Monoclonal Antibodies for Immunocytochemical Characterization of Neural Stem and Differentiated Cells
- Chapter 6Formation of Nervous Systems and Neural Stem Cells in Ascidians
- Chapter 7Regeneration of Brain and Dopaminergic Neurons Utilizing Pluripotent Stem Cells: Lessons from Planarians
- Chapter 8-Secretase-Regulated Signaling Mechanisms: Notch and Amyloid Precursor Protein
- Chapter 9Role of Growth Factor Receptors in Neural Stem Cells Differentiation and Dopaminergic Neurons Generation
- Chapter 10Musashi Proteins in Neural Stem/Progenitor Cells
- Chapter 11Active Expression of Retroelements in Neurons Differentiated from Adult Hippocampal Neural Stem Cells
- Chapter 12Noncoding RNAs in Neural Stem Cell Development
- Chapter 13Neural Stem/Progenitor Cell Clones as Models for Neural Development and Transplantation
- Chapter 14Endogenous Neural Stem/Progenitor Cells and Regenerative Responses to Brain Injury
- Chapter 15Neural Stem Cells: Exogenous and Endogenous Promising Therapies for Stroke
- Chapter 16Ischemia-Induced Neural Stem/Progenitor Cells Within the Post-Stroke Cortex in Adult Brains
- Chapter 17Mesenchymal Stromal Cells and Neural Stem Cells Potential for Neural Repair in Spinal Cord Injury and Human Neurodegenerative Disorders
- Chapter 18Assessing the Influence of Neuroinflammation on Neurogenesis: In Vitro Models Using Neural Stem Cells and Microglia as Valuable Research Tools
- Chapter 19Immune System Modulation of Germinal and Parenchymal Neural Progenitor Cells in Physiological and Pathological Conditions
