Medicine

Neonatal Bacterial Infection

Edited by Bernhard Resch, ISBN 978-953-51-1124-5, 104 pages, Publisher: InTech, Chapters published April 30, 2013 under CC BY 3.0 license
DOI: 10.5772/3317
Edited Volume

Neonatal sepsis still remains a significant cause of morbidity and mortality in the newborn, particularly in preterm, low birth weight infants. Despite advances in neonatal care, overall case-fatality rates from sepsis may be as high as 50%. Clinical signs of bacterial infection are vague and non-specific, and up to now there exists no easily available, reliable marker of infection despite a large bulk of studies focussing on inflammatory indices in neonatology. Every neonatologist is faced with the uncertainty of under- or over- diagnosing bacterial infection. In this book three topics will be discussed: clinical presentation including a general approach to sepsis neonatorum and two distinct diagnoses pneumonia and osteomyelitis diagnostic approaches including C-reactive protein and the immature myeloid information, and prevention and treatment of bacterial infection with immunoglobulins.