Pancreatic Cancer - Molecular Mechanism and Targets

This book provides the reader with an overall understanding of the biology of pancreatic cancer, hereditary, complex signaling pathways and alternative therapies. The book explains nutrigenomics and epigenetics mechanisms such as DNA methylation, which may explain the etiology or progression of pancreatic cancer. Book also summarizes the molecular control of oncogenic pathways such as K-Ras and KL...

This book provides the reader with an overall understanding of the biology of pancreatic cancer, hereditary, complex signaling pathways and alternative therapies. The book explains nutrigenomics and epigenetics mechanisms such as DNA methylation, which may explain the etiology or progression of pancreatic cancer. Book also summarizes the molecular control of oncogenic pathways such as K-Ras and KLF4. Since pancreatic cancer metastasizes to vital organs resulting in poor prognosis, special emphasis is given to the mechanism of tumor cell invasion and metastasis. Role of nitric oxide and Syk kinase in tumor metastasis is discussed in detail. Prevention strategies for pancreatic cancer are also described. The molecular mechanisms of the anti-cancer effects of curcumin, benzyl isothiocyante and vitamin D are discussed in detail. Furthermore, this book covers the basic mechanisms of resistance of pancreatic cancer to chemotherapy drugs such as gemcitabine and 5-flourouracil.

Order Print Copy Recommend to Your Library

Your name

Your email address

Your Library’s email address

Department

Institution/Company

Loading...

Country

Loading...

Message of recommendation Dear Librarian, I would like to recommend the following IntechOpen book to be added to our library catalog: TITLE: 'Pancreatic Cancer - Molecular Mechanism and Targets' PRINT ISBN: 978-953-51-0410-0 Libraries are offered a 20% discount on retail book prices. For a quote, please contact the IntechOpen Print Sales Department directly at orders@intechopen.com Best regards.

I recommend this publication for the following reasons

Loading...

By submitting the form you agree to IntechOpen using your personal information in order to fulfil your library recommendation. In line with our privacy policy we won’t share your details with any third parties and will discard any personal information provided immediately after the recommended institution details are received. For further information on how we protect and process your personal information, please refer to our privacy policy.

Submit