Open access peer-reviewed Edited Volume

Amyotrophic Lateral Sclerosis

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Academic Editor

Martin Henrik Maurer
Martin Henrik Maurer

Heidelberg University

Published20 January 2012

Doi10.5772/1054

ISBN978-953-307-806-9

eBook (PDF) ISBN978-953-51-4379-6

Copyright year2012

Number of pages740

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Table of Contents

Open access  chapters

2. Insights Arising from Gene Expression Profiling in Amyotrophic Lateral Sclerosis

By Johnathan Cooper-Knock, Joanna J. Bury, Laura Ferraiuolo, Emily F. Goodall, Pamela J. Shaw and Janine Kirby

2,116
4. In Vivo and In Vitro Models to Study Amyotrophic Lateral Sclerosis

By François Berthod and François Gros-Louis

5,498
3
5. Advantages and Pitfalls in Experimental Models Of ALS

By Marina Boido, Elisa Buschini, Antonio Piras, Giada Spigolon, Valeria Valsecchi, Letizia Mazzini and Alessandro Vercelli

2,629
2
2,243
7. Molecular and Electrical Abnormalities in the Mouse Model of Amyotrophic Lateral Sclerosis

By Katharina A. Quinlan, Sherif M. Elbasiouny and C.J. Heckman

1,930
8. Role of Mitochondrial Dysfunction in Motor Neuron Degeneration in ALS

By Luz Diana Santa-Cruz, Uri Nimrod Ramírez-Jarquín and Ricardo Tapia

2,814
2
9. Role of Neuronal Mitochondrial Metabolic Phenotype in Pathogenesis of ALS

By Alexander Panov, Nury Steuerwald, Valentin Vavilin, Svetlana Dambinova and Herbert L. Bonkovsky

2,521
11. Folding and Aggregation of Cu, Zn-Superoxide Dismutase

By Helen R. Broom, Heather A. Primmer, Jessica A.O. Rumfeldt, Peter B. Stathopulos, Kenrick A. Vassall, Young-Mi Hwang and Elizabeth M. Meiering

2,605
2
13. Reactive Nitrogen Species in Motor Neuron Apoptosis

By María Clara Franco and Alvaro G. Estévez

2,514
1
15. The Kynurenine Pathway

By Yiquan Chen and Gilles Guillemin

7,571
4
17. Innate Immunity in ALS

By John D. Lee, Jia Y. Lee, Stephen M. Taylor, Peter G. Noakes and Trent M. Woodruff

2,272
18. The Role of TNF-Alpha in ALS: New Hypotheses for Future Therapeutic Approaches

By Cristina Cereda, Stella Gagliardi, Emanuela Cova, Luca Diamanti and Mauro Ceroni

3,511
3
20. Glial Cells as Therapeutic Targets for ALS

By Amanda M. Haidet-Phillips and Nicholas J. Maragakis

2,603
21. Genetics of Amyotrophic Lateral Sclerosis

By Max Koppers, Michael van Es, Leonard H. van den Berg, Jan H. Veldink and R. Jeroen Pasterkamp

2,183
22. Genetics of Familial Amyotrophic Lateral Sclerosis

By Emily F. Goodall, Joanna J. Bury, Johnathan Cooper-Knock, Pamela J. Shaw and Janine Kirby

3,372
25. Assessment and Management of Respiratory Dysfunction in Patients with Amyotrophic Lateral Sclerosis

By Daniele Lo Coco, Paolo Volanti, Domenico De Cicco, Antonio Spanevello, Gianluca Battaglia, Santino Marchese, Alfonsa Claudia Taiello, Rossella Spataro and Vincenzo La Bella

3,606
1
27. How to Assess Disease’s Severity and Monitor Patients with Amyotrophic Lateral Sclerosis: Lessons from Neurophysiology

By Ferdinando Sartucci, Tommaso Bocci, Lucia Briscese, Chiara Pecori, Chiara Rossi and Fabio Giannini

2,227
1

IMPACT OF THIS BOOK AND ITS CHAPTERS

95,221 Total Chapter Downloads

3,953 Total Chapter Views

43 Crossref Citations

89 Web of Science Citations

133 Dimensions Citations

6 Altmetric Score

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