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Hepatocellular Carcinoma - Basic Research
Edited by Wan-Yee Lau, ISBN 978-953-51-0023-2, Hard cover, 402 pages, Publisher: InTech, Published: February 10, 2012 under CC BY 3.0 license, in subject Oncology
DOI: 10.5772/1205
Hepatocellular Carcinoma represents a leading cause of cancer death and a major health problem in developing countries where hepatitis B infection is prevalent. It has also become increasingly important with the increase in hepatitis C infection in developed countries. Knowledge of hepatocellular carcinoma has progressed rapidly. This book is a compendium of papers written by experts to present the most up-to-date knowledge on hepatocellular carcinoma. This book deals mainly with the basic research aspect of hepatocellular carcinoma. The book is divided into three sections: (I) Biomarkers / Therapeutic Target; (II) Carcinogenesis / Invasion / Metastasis; and (III) Detection / Prevention / Prevalence. There are 18 chapters in this book. This book is an important contribution to the basic research of hepatocellular carcinoma. The intended readers of this book are scientists and clinicians who are interested in research on hepatocellular carcinoma. Epidemiologists, pathologists, hospital administrators and drug manufacturers will also find this book useful.
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Book contents
- Chapter 1LAPTM4B: A Novel Diagnostic Biomarker and Therapeutic Target for Hepatocellular Carcinoma
- Chapter 2Novel Therapeutic Targets for Hepatocellular Carcinoma Treatment
- Chapter 3Clinical Significance of Serum Ornithine Carbamoyltransferase in Liver Diseases – Is the Ratio of OCT/ALT a New Tumor Marker?
- Chapter 4New Molecular Biomarkers Candidates for the Development of Multiparametric Platforms for Hepatocellular Carcinoma Diagnosis, Prognosis and Personalised Therapy
- Chapter 5Modulation of Cell Proliferation Pathways by the Hepatitis B Virus X Protein: A Potential Contributor to the Development of Hepatocellular Carcinoma
- Chapter 6Vascular Adhesion Protein-1 and Hepatocellular Cancer
- Chapter 7Tissue Factor Pathway Inhibitor-2 Inhibits the Growth and Invasion of Hepatocellular Carcinoma Cells and is Inactivated in Human Hepatocellular Carcinoma
- Chapter 8Proteoglycans in Chronic Liver Disease and Hepatocellular Carcinoma: An Update
- Chapter 9Chemically Induced Hepatocellular Carcinoma and Stages of Development with Biochemical and Genetic Modulation: A Special Reference to Insulin-Like-Growth Factor II and Raf Gene Signaling
- Chapter 10Hepatocellular Carcinoma: Insights from the Centrosome Abnormalities
- Chapter 11Cytoplasmic Connexin32 and Self-Renewal of Cancer Stem Cells: Implication in Metastasis
- Chapter 12The Involvement of the ERK-Hypoxia-Angiogenesis Signaling Axis and HIF-1 in Hepatocellular Carcinoma
- Chapter 13Gap Junction Intercellular Communication and Connexin Expression Profile in Normal Liver Cells and Hepatocarcinoma
- Chapter 14Mechanisms of HBx Mediated Liver Cancer: Multiple Pathways and Opportunities
- Chapter 15Molecular Mechanism of DNA Damage Response Pathway During Hepatic Carcinogenesis
- Chapter 16Hepatocellular Carcinoma: Methods of Circulating Tumor Cells (CTC) Measurements
- Chapter 17Use of a Human–Derived Liver Cell Line for the Detection of Protective Effect of Dietary Antioxidants against Food Mutagens
- Chapter 18Reviews on the Epidemiology, Quality of Life, and Management of Chronic Hepatitis B (CHB)
