Biochemistry, Genetics and Molecular Biology

Fundamental Aspects of DNA Replication

Edited by Jelena Kušić-Tišma, ISBN 978-953-307-259-3, 318 pages, Publisher: InTech, Chapters published September 26, 2011 under CC BY-NC-SA 3.0 license
DOI: 10.5772/766
Edited Volume

DNA replication, the process of copying one double stranded DNA molecule to produce two identical copies, is at the heart of cell proliferation. This book highlights new insights into the replication process in eukaryotes, from the assembly of pre-replication complex and features of DNA replication origins, through polymerization mechanisms, to propagation of epigenetic states. It also covers cell cycle control of replication initiation and includes the latest on mechanisms of replication in prokaryotes. The association between genome replication and transcription is also addressed. We hope that readers will find this book interesting, helpful and inspiring.