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Chemical Biology
Edited by Deniz Ekinci, ISBN 978-953-51-0049-2, Hard cover, 444 pages, Publisher: InTech, Published: February 17, 2012 under CC BY 3.0 license, in subject Pharmacology, Toxicology and Pharmaceutical Science
DOI: 10.5772/2625
Chemical biology utilizes chemical principles to modulate systems to either investigate the underlying biology or create new function. Over recent years, chemical biology has received particular attention of many scientists in the life sciences from botany to medicine. This book contains an overview focusing on the research area of protein purification, enzymology, vitamins, antioxidants, biotransformation, gene delivery, signaling, regulation and organization. Particular emphasis is devoted to both theoretical and experimental aspects. The textbook is written by international scientists with expertise in synthetic chemistry, protein biochemistry, enzymology, molecular biology, drug discovery and genetics many of which are active chemical, biochemical and biomedical research. The textbook is expected to enhance the knowledge of scientists in the complexities of chemical and biological approaches and stimulate both professionals and students to dedicate part of their future research in understanding relevant mechanisms and applications of chemical biology.
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Book contents
- Chapter 1Protein Purification
- Chapter 2The Problems Associated with Enzyme Purification
- Chapter 3Nicotinamide Phosphoribosyltransferase Inhibitors
- Chapter 4Cofactor Recycling Using a Thermostable NADH Oxidase
- Chapter 5Analyses of Sequences of (β/α) Barrel Proteins Based on the Inter-Residue Average Distance Statistics to Elucidate Folding Processes
- Chapter 6Functional Implication Guided by Structure-Based Study on Catalase – Peroxidase (KatG) from Haloarcula Marismortui
- Chapter 7Effects of Dietary Fortification of Vitamin A and Folic Acid on the Composition of Chicken Egg
- Chapter 8Mitochondria and Antioxidants: The Active Players in Islet Oxidative Stress
- Chapter 9Nitric Oxide Signaling During Senescence and Programmed Cell Death in Leaves
- Chapter 10Menaquinone as Well as Ubiquinone as a Crucial Component in the Escherichia coli Respiratory Chain
- Chapter 11Genetically Modified Baker’s Yeast Saccharomyces cerevisiae in Chemical Synthesis and Biotransformations
- Chapter 12Animal Models for Hydrodynamic Gene Delivery
- Chapter 13Role of β-Arrestins in Endosomal Sorting of G Protein-Coupled Receptors
- Chapter 14Structure and Function of the Lipolysis Stimulated Lipoprotein Receptor
- Chapter 15Ghrelin, a Gastric Hormone with Diverse Functions
- Chapter 16Polysialylation of the Neural Cell Adhesion Molecule: Setting the Stage for Plasticity Across Scales of Biological Organization
- Chapter 17What Does Maurocalcine Tell Us About the Process of Excitation-Contraction Coupling?
- Chapter 1813C-Metabolic Flux Analysis and Metabolic Regulation
- Chapter 19QCM as Cell-Based Biosensor
