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This book is indexed in
Medicine » Oncology
Breast Cancer - Carcinogenesis, Cell Growth and Signalling Pathways
Edited by Mehmet Gunduz and Esra Gunduz, ISBN 978-953-307-714-7, Hard cover, 732 pages, Publisher: InTech, Chapters published November 30, 2011 under CC BY 3.0 license
DOI: 10.5772/855
Cancer is the leading cause of death in most countries and its consequences result in huge economic, social and psychological burden. Breast cancer is the most frequently diagnosed cancer type and the leading cause of cancer death among females. In this book, we discussed various aspects of breast cancer carcinogenesis from clinics to its hormone-based as well as genetic-based etiologies for this deadly cancer. We hope that this book will contribute to the development of novel diagnostic as well as therapeutic approaches.
- Chapter 1
EGFR-Ligand Signaling in Breast Cancer Metastasis: Recurring Developmental Themes - Chapter 2
EGF Regulation of HRPAP20: A Role for Calmodulin and Protein Kinase C in Breast Cancer Cells - Chapter 3
Endocytic Trafficking of the Epidermal Growth Factor Receptor in Transformed Cells - Chapter 4
HER-2 Signaling in Human Breast Cancer - Chapter 5
Brain Metastases Progression of Breast Cancer - Chapter 6
Signal Transduction Pathways in Breast Cancer – Drug Targets and Challenges - Chapter 7
ErbB2/HER2: Its Contribution to Basic Cancer Biology and the Development of Molecular Targeted Therapy - Chapter 8
Trastuzumab-Resistance and Breast Cancer - Chapter 9
Targeting HER-2 Signaling Network: Implication in Radiation Response - Chapter 10
The Importance of ERα/ERβ Ratio in Breast Cancer: Mitochondrial Function and Oxidative Stress - Chapter 11
Heterogeneity of Phenotype in Breast Cancer Cell Lines - Chapter 12
Metabolomics and Transcriptional Responses in Estrogen Receptor Positive Breast Cancer Cells - Chapter 13
ER-Alpha36 Mediates Non-Genomic Estrogen and Anti-Estrogen Signaling in Breast Cancer Cells - Chapter 14
Estrogen-Related Receptors and Breast Cancer: A Mini Review - Chapter 15
The Role of MicroRNAs in Estrogen Receptor α-Positive Human Breast Cancer - Chapter 16
Roles of SWI/SNF Complex Genes in Breast Cancer - Chapter 17
p53, p63 and p73 Network in Breast Cancers - Chapter 18
Role of ING Family Tumor Suppressors in Breast Cancer - Chapter 19
Lipid Rafts as Master Regulators of Breast Cancer Cell Function - Chapter 20
Differences in Membrane Composition and Organization of Crucial Molecules Define the Invasive Properties of MCF-7 Breast Cancer Cells - Chapter 21
Adipose Tissue and Desmoplastic Response in Breast Cancer - Chapter 22
Cross-Talk of Breast Cancer Cells with the Immune System - Chapter 23
Engineering Transcription Factors in Breast Cancer Stem Cells - Chapter 24
Breast Cancer Stem Cells – A Review - Chapter 25
Potential Roles of miR-106a in Breast Cancer - Chapter 26
Scleroderma and Breast Cancer - Chapter 27
FZD7 in Triple Negative Breast Cancer Cells - Chapter 28
Dysregulation of Wnt Signaling in Breast Cancer - Chapter 29
Interactions of STAP-2 with BRK and STAT3/5 in Breast Cancer Cells - Chapter 30
Histamine and Breast Cancer: A New Role for a Well Known Amine - Chapter 31
1,25(OH)2D3 and Cyclooxygenase-2: Possible Targets for Breast Cancer? - Chapter 32
Calcium, Ca2+-Sensing Receptor and Breast Cancer - Chapter 33
Signal Transduction Pathways Mediated by Unsaturated Free Fatty Acids in Breast Cancer Cells - Chapter 34
Adrenoceptors and Breast Cancer: Review Article - Chapter 35
Steroid Receptor Coactivators and Their Expression, Regulation and Functional Role in Endocrine Responsive and Resistant Breast Cancer


