Biochemistry, Genetics and Molecular Biology

Advances in Immunoassay Technology

Edited by Norman H. L. Chiu and Theodore K. Christopoulos, ISBN 978-953-51-0440-7, 180 pages, Publisher: InTech, Chapters published March 23, 2012 under CC BY 3.0 license
DOI: 10.5772/1967

From the basic in vitro study of a specific biomolecule to the diagnosis or prognosis of a specific disease, one of the most widely used technology is immunoassays. By using a specific antibody to recognize the biomolecule of interest, relatively high specificity can be achieved by immunoassays, such that complex biofluids (e.g. serum, urine, etc.) can be analyzed directly. In addition to the binding specificity, the other key features of immunoassays include relatively high sensitivity for the detection of antibody-antigen complexes, and a wide dynamic range for quantitation. Over the past decade, the development and applications of immunoassays have continued to grow exponentially. This book focuses on some of the latest technologies for the development of new immunoassays.