Medicine » Immunology, Allergology and Rheumatology

A Look into Myasthenia Gravis

Edited by Joseph A. Pruitt, ISBN 978-953-307-821-2, 114 pages, Publisher: InTech, Chapters published January 20, 2012 under CC BY 3.0 license
DOI: 10.5772/1243
Edited Volume

Myasthenia gravis is presently an incurable antibody-mediated autoimmune disorder characterized by generalized voluntary skeletal muscle weakness. The cause of the weakness is a defect at the neuromuscular junction level, in which autoimmune antibodies block the receptors responsible for initiating muscular contraction. Literally translated from its Latin and Greek etymological roots, myasthenia gravis means "grave muscle weakness". Fortunately, advances in modern medicine have resulted in a reduction of the truly "grave" outcomes for those inflicted but, without a cure, the gravity surrounding the disease remains