Chapters authored
Contraception and Family Planning: New Aspects Related to the Therapeutic Possibilities
The therapeutic use of CHC (combined hormonal contraception) is examined in healthy patients who accept this contraceptive method and in patients with specific problems (abundant menstrual flows, hyperandrogenism, chronic pelvic pain, PMS, disability, different lifestyles, etc.) who require contraception. Rational motivation for the non-only contraceptive use of this device is represented by their mechanism of action: antigonadotropic action with ovulatory block and reduced production of sex steroids, endometrial response with changes in menstrual bleeding, action on the progesterone receptor, downregulation of estrogen receptors, and anti-inflammatory action. The dosing regimen (continuous regimen) can also modulate the therapeutic response in relation to the utilization in pathologies with catamenial exacerbation. The metabolic response varies in relation to the characteristics of the association (synthetic or natural estrogen, progestin component) with possible hepatocellular action, characteristic for associations with EE. Numerous data on associations with EE, few data with natural estrogens are available; the assumptions of use in relation to particular therapeutic lines are examined.
Part of the book: Conception and Family Planning